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2015 Publications

 

Chaston, J.J., Smits, C., Aragão, D., Wong, A.S., Ahsan, B., Sandin, S., Molugu, S.K., Molugu, S.K., Bernal, R.A., Stock, D. and Stewart, A.G.

Structural and Functional Insights into the Evolution and Stress Adaptation of Type II Chaperonins.

Structure, 16 Dec 2015; doi: https://doi.org/10.1016/j.str.2015.12.016

 

 

Qu, J., Ero, R., Feng, C., Ong, L.T., Tan, H.F., Lee, H.S., Ismail, M.H., Bu, W.T., Nama, S., Sampath, P. and Gao, Y.G.

Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells.

Scientific reports, 18 Dec 2015; doi: https://doi.org/10.1038/srep18491

 

 

Singh, D., Sielaff, H., Sundararaman, L., Bhushan, S. and Grüber, G.

The stimulating role of subunit F in ATPase activity inside the A1-complex of the Methanosarcina mazei Gö1 A1AO ATP synthase.

Biochimica et Biophysica Acta – Bioenergetics, 9 Dec 2015 ; doi: https://doi.org/10.1016/j.bbabio.2015.12.003

 

 

Zhao, Y., Soh, T.S., Lim, S.P., Chung, K.Y., Swaminathan, K., Vasudevan, S.G., Shi, P.Y., Lescar, J. and Luo, D.

Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5). 

Proceedings of the National Academy of Sciences, 17 Nov 2015; doi: https://doi.org/10.1073/pnas.1514978112

 

 

Tsai, Y.C.C., Lapina, M.C., Bhushan, S. and Mueller-Cajar, O.

Identification and characterization of multiple rubisco activases in chemoautotrophic bacteria. 

Nature communications, 16 Nov 2015; doi: https://doi.org/10.1038/ncomms9883

 

 

Cheong, V.V., Lech, C.J., Heddi, B. and Phan, A.T.

Inverting the G-Tetrad Polarity of a G-Quadruplex by Using Xanthine and 8-Oxoguanine

Angewandte Chemie International Edition, 13 Nov 2015; doi: https://doi.org/10.1002/anie.201507034

 

 

Rhodes, D. and Lipps, H.J.

G-quadruplexes and their regulatory roles in biology.

Nucleic acids research, 10 Oct 2015; doi: https://doi.org/10.1093/nar/gkv862

 

 

Li, Y., Kim, Y.M., Zou, J., Wang, Q.Y., Gayen, S., Wong, Y.L., Xie, X., Huang, Q., Lescar, J., Shi, P.Y. and Kang, C.

Secondary structure and membrane topology of dengue virus NS4B N-terminal 125 amino acids. 

Biochimica et Biophysica Acta (BBA)-Biomembranes, 25 Sep 2015; doi: https://doi.org/10.1016/j.bbamem.2015.09.016

 

 

Lee, R.F., Escrig, S., Croisier, M., Clerc-Rosset, S., Knott, G.W., Meibom, A., Davey, C.A., Johnsson, K. and Dyson, P.J.

NanoSIMS Analysis of an Isotopically Labelled Organometallic Ruthenium(II) Drug to Probe Its Distribution and State In Vitro.  

Chemical Communications, 23 Sep 2015; doi: https://doi.org/10.1039/C5CC06983A

 

 

Cheong, V.V., Heddi, B., Lech, C.J. and Phan, A.T.

Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G· G· X· O tetrad.

Nucleic acids research, 22 Sep 2015; doi: https://doi.org/10.1093/nar/gkv826

 

 

Ye, F., Wang, C., Fu, Q., Zhang, L.H. and Gao, Y.G.

Cloning, expression, purification and crystallization of a pair of novel virulence factors, SghA and SghR, from Agrobacterium tumefaciens. 

Acta Crystallographica Section F: Structural Biology Communications, 25 Aug 2015; doi: https://doi.org/10.1107/S2053230X15012881

 

 

Kumar, V., Chen, Y., Ero, R., Ahmed, T., Tan, J., Li, Z., Wong, A.S.W., Bhushan, S. and Gao, Y.G.

Structure of BipA in GTP form bound to the ratcheted ribosome.

Proceedings of the National Academy of Sciences, 17 Aug 2015; doi: https://doi.org/10.1073/pnas.1513216112

 

 

Zhao, Y., Soh, T.S., Chan, K.W.K., Fung, S.S.Y., Swaminathan, K., Lim, S.P., Shi, P.Y., Huber, T., Lescar, J., Luo, D. and Vasudevan, S.G.

Flexibility of NS5 methyltransferase-polymerase linker region is essential for dengue virus replication.

Journal of virology, 12 Aug 2015; doi: 10.1128/JVI.01239-15

 

 

Wang, C., Yan, C., Gao, Y.G. and Zhang, L.H.

D101 is critical for the function of AttJ, a repressor of quorum quenching system in Agrobacterium tumefaciens.

Journal of Microbiology, 1 Aug 2015; doi: https://doi.org/10.1007/s12275-015-5100-x

 

 

Heddi, B., Cheong, V.V., Martadinata, H. and Phan, A.T.

Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide–quadruplex complex.

Proceedings of the National Academy of Sciences, 20 Jul 2015; doi: https://doi.org/10.1073/pnas.1422605112

 

 

Robinson, L.N., Tharakaraman, K., Rowley, K.J., Costa, V.V., Chan, K.R., Wong, Y.H., Ong, L.C., Tan, H.C., Koch, T., Cain, D., Kirloskar, R., Viswanathan, K., Liew, C.W., TIssire, H., Ramakrishnan, B., Myette, J.R., Babcock, G.J., Sasisekharan, V., Alonso, S., Chen, J., Lescar, J., Shriver, Z., Ooi, E.E. and Sasisekharan R.

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.

Cell. 16 Jul 2015; doi: https://doi.org/10.1016/j.cell.2015.06.057

 

 

Wu, B. and Hur, S.

How RIG-I like receptors activate MAVS.

Current opinion in virology, 13 May 2015; doi: https://doi.org/10.1016/j.coviro.2015.04.004

 

 

Lim, K.W., Jenjaroenpun, P., Low, Z.J., Khong, Z.J., Ng, Y.S., Kuznetsov, V.A. and Phan, A.T.

Duplex stem-loop-containing quadruplex motifs in the human genome: a combined genomic and structural study.

Nucleic acids research, 9 May 2015; doi: https://doi.org/10.1093/nar/gkv355

 

 

Piazza, A., Adrian, M., Samazan, F., Heddi, B., Hamon, F., Serero, A., Lopes, J., TeuladeFichou, M.P., Phan, A.T. and Nicolas, A.

Short loop length and high thermal stability determine genomic instability induced by Gquadruplexforming minisatellites.

The EMBO journal, 8 May 2015; doi: https://doi.org/10.15252/embj.201490702

 

 

Chua, E.Y., Davey, G.E., Chin, C.F., Dröge, P., Ang, W.H. and Davey, C.A.

Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.

Nucleic acids research, 27 Apr 2015; doi: https://doi.org/10.1093/nar/gkv356

 

 

Luo, D., Vasudevan, S.G. and Lescar, J.

The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development.

Antiviral research, 2 Apr 2015; doi: https://doi.org/10.1016/j.antiviral.2015.03.014

 

 

Zhao, Y., Soh, T.S., Zheng, J., Chan, K.W., Phoo, W.W., Lee, C.C., Tay, M.Y., Swaminathan, K., Cornvik, T.C., Lim, S.P., Shi, P.Y., Lescar, J., Vasudevan, S.G. and Luo, D.

A crystal structure of the Dengure virus NS5 protein reveals a novel inter-domain interface essential for protein flexbility and virus replication.

PLoS Pathogens, 16 Mar 2015; doi: 10.1371/journal.ppat.1004682

 

 

Ero, R., Dimitrova, V.T., Chen, Y., Bu, W., Feng, S., Liu, T., Wang, P., Xue, C., Tan, S.M. and Gao, Y.G.

Crystal structure of Gib2, a signal-transducing protein scaffold associated with ribosomes in Cryptococcus neoformans. 

Scientific Reports, 3 Mar 2015; doi: https://doi.org/10.1038/srep08688

 

 

Davey, C.A.

Exposure to metals can be therapeutic.

CHIMIA International Journal for Chemistry, 1  Mar 2015; doi: https://doi.org/10.2533/chimia.2015.125

 

Allahverdi, A., Chen, Q., Korolev, N. and Nordenskiöld, L.

Chromatin compaction under mixed salt conditions: opposite effects of sodium and potassium ions on nucleosome array folding.

Scientific reports, 17 Feb 2015; doi: https://doi.org/10.1038/srep08512

 

 

Lyubartsev, A.P., Korolev, N., Fan, Y. and Nordenskiöld, L.

Multiscale modelling of nucleosome core particle aggregation.

Journal of Physics: Condensed Matter, 7 Jan 2015; doi: https://doi.org/10.1088/0953-8984/27/6/064111

 

 

Zheng, J., Yong, H.Y., Panutdaporn, N., Liu, C., Tang, K. and Luo, D.

High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5.

Nucleic acids research, 24 Dec 2014; doi: https://doi.org/10.1093/nar/gku1329

 

 

Tay, M.Y., Saw, W.G., Zhao, Y., Chan, K.W., Singh, D., Chong, Y., Forwood, J.K., Ooi, E.E., Grüber, G., Lescar, J., Luo, D. and Vasudevan, S.G.

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.

Journal of Biological Chemistry, 8 Dec 2014; doi: 10.1074/jbc.M114.607341

 

 

Toh, J.D., Sun, L., Lau, L.Z., Tan, J., Low, J.J., Tang, C.W., Cheong, E.J., Tan, M.J., Chen, Y., Hong, W. and Gao, Y.G.

A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N 6-methyladenosine demethylase FTO. 

Chemical science, 22 Sep 2014; doi: 10.1039/C4SC02554G

 

 

Wang, C., Ye, F., Kumar, V., Gao, Y.G. and Zhang, L.H.

BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ. 

Nucleic acids research, 31 Jan 2014; doi: https://doi.org/10.1093/nar/gku106