2015 Publications


Qu J, Ero R, Feng C, Ong LT, Tan HF, Ismail MH, Bu WT, Nama S, Sampth P, Gao YG, Tan SM.
Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells.​
Sci Rep. 2015 Dec;5:18491​​

Zhao Y, Soh TS, Lim SP, Chung KY, Swaminathan K, Vasudevan SG, Shi PY, Lescar J, Luo D.
Proc Natl Acad Sci U S A. 2015 Dec;112(48):14834-9.​

Li Y, Kim YM, Zou J, Wang QY, Gayen S, Wong YL, Lee LT, Xie X, Huang Q, Lescar J, Shi PY, Kang C.
Biochim Biophys Acta. 2015 Dec;1848(12):3150-7​

Cheong VV, Heddi B, Lech CJ, Phan AT.
Nucleic Acids Res. 2015 Dec;43(21):10506-14.​

Lee RF, Escrig S, Croisier M, Clerc-Rosset S, Knott GW, 
NanoSIMS Analysis of an Isotopically Labelled Organometallic Ruthenium (ll) Drug to Probe its Distribution and State in Vitro.​
Chem Commun (Camb). 2015 Nov;51(92):16486-9.

Tsai YC, Lapina MC, Bhushan S, Mueller-Cajar O.
Identification and characterization of multiple rubisco activases in chemoautotrophic bacteria.​
Nat Commun. 2015 Nov;6:8883.​​​

Zhao Y, Soh TS, Chan KW, Fung SS, Swaminathan K, Lim SP, Shi PY, Huber T, Lescar J, Luo D, Vasudevan SG.
Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication.​
J Virol. 2015 Oct;89(20):10717-21. ​​

Rhodes D, Lipps H.
G-quadruplexes and their regulatory roles in biology.​
Nucleic Acids Res. 2015 Oct;43(18):8627-37.​

Wang C, Yan C, Gao YG, Zhang L.
D101 is critical for the function of AttJ, a repressor of quorum quenching system in Agrobacterium tumefaciens.​
J Microbiol. 2015 Sep;53(9):623-32. ​​

Kumar V, Chen Y, Ero R, Ahmed T, Tan J, Li Z, Wong AS, Bhusan S, Gao YG.
Structure of BipA in GTP form bound to the ratcheted ribosome.​​
Proc Natl Acad Sci U S A. 2015 Sep;112(35):10944-9.​​

​​Heddi B, Cheong VV, Martadinata H, Phan AT.​
Insights into G-Quadruplex Specific Recognition by the DEAH-box Helicase RHAU: Solution Structure of a Peptide-Quadruplex Complex.​
Proc Natl Acad Sci U S A. 2015 Aug;112(31):9608-13​

Robinson LN, Tharakaraman K, Rowley KJ, Costa VV, Chan KR, Wong YH, Ong LC, Tan HC, Koch T, Cain D, Kirloskar R, Viswanathan K, Liew CW, TIssire H, Ramakrishnan B, Myette JR, Babcock GJ, Sasisekharan V, Alonso S, Chen J, Lescar J, Shriver Z, Ooi EE, Sasisekharan R.
Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.​​
Cell. 2015 Jul 30;162(3):493-504.

Luo D, Vasudevan SG, Lescar J.
The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development.​​
Antiviral Res. 2015 Jun;118:148-58​​

Wu B, Hur S.​
How RIG-I like receptors activate MAVS.​
Curr Opin Virol. 2015 Jun;12:91-8.​

Chua YD, Davey GE, Chin CF,  Dröge P, Ang WH, Davey CA.
Stereochemical Control of Nucleosome Targeting by Platinum-intercalator Antitumor Agents.
Nucleic Acids Res. 2015 Jun;43(11):5284-96

Lim KW, Jenjaroenpun P, Low ZJ, Khong ZJ, Ng YS, Kuznetsov VA, Phan AT.
Duplex Stem-loop-containing Quadruplex Motifs in the Human Genome: A Combined Genomic and Structural Study.
Nucleic Acids Res. 2015 Jun;43(11):5630-46.​​

Piazza A, Adrian M, Samazan F, Heddi B, Hamon F, Serero A, Lopes J, Teulade-Fichou MP, Phan AT, Nicolas A.
Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites.​
EMBO J. 2015 Jun;34(12):1718-34.​

CA Davey
Exposure to Metals Can Be Therapeutic.
Chimia (Aarau). 2015 Mar;69(3):125-30.​​

Zhao Y, Soh TS, Zheng J, Chan KW, Phoo WW, Lee CC, Tay MY, Swaminathan K, Cornvik TC, Lim SP, Shi PY, Lescar J, Vasudevan SG, Luo D.
A crystal structure of the Dengure virus NS5 protein reveals a novel inter-domain interface essential for protein flexbility and virus replication.
PLoS Pathog. 2015 Mar;11(3):e1004682​

Ero R, Dimitrova VT, Chen Y, Bu W, Feng S, Liu T, Wang P, Xue C, Tan SM, Gao YG.
Crystal structure of Gib2, a signal-transducing protein scaffold associated with ribosomes in Cryptococcus neoformans.
Sci Rep. 2015 Mar;5:8688.​

Allahverdi A, Chen Q, Korolev N,  Nordenskiöld L.
Chromatin Compaction Under Mixed Salt Conditions: Opposite Effects of Sodium and Potassium Ions on Nucleosome Array Folding.​
Sci Rep. 2015 Feb;5:8512.​

Lyubartsev AP, Korolev N, Fan Y, Nordenskiöld L
Multiscale Modelling of Nucleosome Core Particle Aggregation.​
J Phys Condens Matter. 2015 Feb 18;27(6):064111

Tay MY, Saw WG, Zhao Y, Chan KW, Singh D, Chong Y, Forwood JK, Ooi EE,  Grüber G, Lescar J, Luo D, Vasudevan SG.
The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.​
J Biol Chem. 2015 Jan;290(4):2379-94.​​​

Zheng J, Yong HY, Panutdaporn N, Liu C, Tang K, Luo D.
High-resolution HDX-MS reveals distinct mechanisms of RNA recogition and activation by RIG-I and MDA5​
Nucleic Acids Res. 2015 Jan;43(2):1216-30.​