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2016 Publications


 

 

Peng, M., Watanabe, S., Chan, K. W. K., He, Q., Zhao, Y., Zhang, Z., Xiaoping, L., Dahai, L., Subhash, G. V., and Li, G. 

Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin. 

Antiviral Research, 5 Apr 2017; doi: https://doi.org/10.1016/j.antiviral.2017.03.026

 

 

Adhireksan, Z., Palermo, G., Riedel, T., Ma, Z., Muhammad, R., Rothlisberger, U., Dyson, P. J. and Davey, C. A.

Allosteric cross-talk in chromatin can mediate drug-drug synergy.  

Nature Communications, 30 Mar 2017; doi: https://doi.org/10.1038/ncomms14860

 

 

Bi, X., Pasunooti, K. K., Lescar J. and Liu, C. F. 

Thiazolidine-masked α-oxo aldehyde functionality for peptide and protein modification.  

Bioconjugate Chemistry, 15 Feb 2017; doi: https://doi.org/10.1021/acs.bioconjchem.6b00667

 

 

Davies, R.B., Smits, C., Wong, A.S.W., Stock, D., Christie, M., Sandin, S. and Stewart, A.G. 

Cryo-EM analysis of a domain antibody bound rotary ATPase complex. 

Journal of structural biology, 20 Jan 2017; doi: https://doi.org/10.1016/j.jsb.2017.01.002

 

 

Sobti, M., Smits, C., Wong, A. S., Ishmukhametov, R., Stock, D., Sandin, S. and Stewart, A. G. 

Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states.  

Elife, 21 Dec 2016 ; doi: https://doi.org/10.7554/eLife.21598.001

 

 

Lim, S.K., Wong, A.S., de Hoog, H.M., Rangamani, P., Parikh, A.N., Nallani, M., Sandin, S. and Liedberg, B. 

Spontaneous formation of nanometer scale tubular vesicles in aqueous mixtures of lipid and block copolymer amphiphiles.  

Soft matter, 9 Dec 2016; doi: https://doi.org/10.1039/C6SM01753C

 

 

Zhang, Z., Li, Y., Loh, Y. R., Phoo, W. W., Hung, A.W., Kang, C. and Luo, D. 

Crystal structure of unlinked NS2B-NS3 protease from Zika virus. 

Science, 8 Dec 2016; doi: 10.1126/science.aai9309

 

 

Jin, S., Sun, J., Wunder, T., Tang, D., Cousins, A. B., Sze, S. K., Mueller-Cajar, O. and Gao, Y.G. 

Structural insights into the LCIB protein family reveals a new group of β-carbonic anhydrases. 

Proceedings of the National Academy of Sciences,  1 Dec 2016; doi: https://doi.org/10.1073/pnas.1616294113

 

 

Ero, R., Kumar, V., Chen, Y. and Gao, Y.G.

Similarity and diversity of translational GTPase factors EF-G, EF4, and BipA: From structure to function. 

RNA Biology, 14 Nov 2016; doi: https://doi.org/10.1080/15476286.2016.1201627

 

 

Ahmed, T., Yin, Z., and Bhushan, S.

Cryo-EM structure of the large subunit of the spinach chloroplast ribosome. 

Scientific Reports, 20 Oct 2016; doi: https://doi.org/10.1038/srep35793

 

 

Chua, E.Y., Vogirala, V. K., Inian, O., Wong, A. S., Nordenskiöld, L., Plitzko, J. M., Danev, R. and Sandin, S.

3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM. 

Nucleic Acids Research, 30 Sep 2016; doi: https://doi.org/10.1093/nar/gkw708

 

 

Jaroensuk, J., Atichartpongkul, S., Chionh, Y. H., Wong, Y. H., Liew, C. W., McBee, M. E., Thongdee, N., Prestwich, E. G., DeMott, M. S., Mongkolsuk, S., Dedon, P. C., Lescar, J. and Fuangthong, M. 

Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa. 

Nucleic Acids Research, 28 Sep 2016; doi: https://doi.org/10.1093/nar/gkw870

 

 

Li, Y., Wong, Y. L., Lee, M. Y., Li, Q., Wang, Q. Y., Lescar, J., Shi, P. Y. and Kang C. 

Secondary Structure and Membrane Topology of the Full-Length Dengue Virus NS4B in Micelles.  

Angewandte Chemie, 24 Aug 2016; doi: https://doi.org/10.1002/ange.201606609

 

 

Sandin, S., Danev, R., Plitzko, J. M., Dao, E. C. Y., Vogirala, V. K., and Wong, A. S. W. 

High-resolution Imaging of Reconstituted Protein-DNA Complexes Using Phase Plate Electron Cryo Microscopy. 

Microscopy and Microanalysis, 25 July 2016; doi: https://doi.org/10.1017/S1431927616001197

 

 

Ma, Z., Palermo, G., Adhireksan, Z., Murray, B.S., Von Erlach, T., Dyson, P.J., Rothlisberger, U. and Davey, C.A. 

An Organometallic Compound Which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.  

Angewandte Chemie International Edition, 17 May 2016; doi: https://doi.org/10.1002/anie.201602145

 

 

Zou, S., Toh, J.D., Wong, K.H., Gao, Y.G., Hong, W. and Woon, E.C.

N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 

Scientific Reports, 9 May 2016; doi: https://doi.org/10.1038/srep25677

 

 

Kumar, V., Ero, R., Ahmed, T., Goh, K.J., Zhan, Y., Bhushan, S. and Gao, Y.G.

Structure of the GTP Form of Elongation Factor (EF4) Bound to the Ribosome. 

Journal of Biological Chemistry, 2 May 2016; doi: 10.1074/jbc.M116.725945

 

 

Hernández-Hernández, A., Masich, S., Fukuda, T., Kouznetsova, A., Sandin, S., Daneholt, B., and Höög, C. 

The central element of the synaptonemal complex in mice is organized as a bilayered junction structure.  

Journal of Cell Science, 14 Apr 2016; doi: 10.1242/jcs.182477

 

 

Vijaya, C. S. H., Makhija, H., Peter, S., Myint, W. C. M., Li, J., Zhu, J., Ren, Z.,  D'Alcontres, M. S., Siau, J. W., Chee, S., Ghadessy, F. J. and  Dröge, P. 

Conservative site-specific and single-copy transgenesis in human LINE-1 elements 

Nucleic Acids Research, 7 April 2016; doi: https://doi.org/10.1093/nar/gkv1345

 

 

Qian, X., Hamid, F.M., El Sahili, A., Darwis, D.A., Wong, Y.H., Bhushan, S., Makeyev, E.V. and Lescar, J.

Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA Polymerases.

Journal of Biological Chemistry, 23 Feb 2016; doi: 10.1074/jbc.M115.685933

 

 

Wu, B., Huoh, Y. S., and Hur, S. 

Measuring Monomer-to-Filament Transition of MAVS as an In Vitro Activity Assay for RIG-I-Like Receptors. 

Methods in Molecular Biology, 24 Jan 2016; doi: https://doi.org/10.1007/978-1-4939-3335-8_9

 

 

Tay, M. Y., Smith, K., Ng, I. H., Chan, K. W., Zhao, Y., Ooi, E. E., Lescar, J., Luo, D., Jans, D.A., Forwood, J.K.  and Vasudevan, S. G.  

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. 

PLoS Pathogens 13 Sep 2016 Sep; doi: 10.1371/journal.ppat.1005886

 

 

Ludwig, A., Nichols, B.J. and Sandin, S.

Architecture of the caveolar coat complex. 

Journal of Cell Science, 15 Aug 2016; doi: 10.1242/jcs.191262

 

 

Lim, S. P., Noble, C. G., Seh, C. C., Soh, T. S., El Sahili, A., Chan, G. K., Lescar, J., Arora, R., Benson, T., Nilar, S., Manjunatha, U., Wan, K. F., Dong, H., Xie, X., Shi, P. Y., and Yokokawa, F.  

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling. 

PLoS pathogens, 12 Aug 2016; doi: https://doi.org/10.1371/journal.ppat.1005737

 

 

Palermo, G., Magistrato, A., Riedel, T., Von Erlach, T., Davey, C.A., Dyson, P.J. and Rothlisberger, U.

Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies.  

ChemMedChem, 4 Dec 2015; doi: https://doi.org/10.1002/cmdc.201500478


 

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