Publications

Share            

2018 Publications

 

Tie HC, Ludwig A, Sandin S, Lu L.

The spatial separation of processing and transport functions to the interior and periphery of the Golgi stack.

Elife. 2018 Nov 30;7.

 

 

Ivanyi-Nagy R, Ahmed SM, Peter S, Ramani PD, Ong PF, Dreesen O, Dröge P.

The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis.

Elife. 2018 Oct 25;7. pii: e40037. doi: 10.7554/eLife.40037.

 

 

Peng M, Swarbrick CMD, Chan KW, Luo D, Zhang W, Lai X, Li G, Vasudevan SG.

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation.

Antiviral Res. 2018 Jun;154:87-96. doi:10.1016/j.antiviral.2018.04.013.

 

 

Phoo WW, Zhang Z, Wirawan M, Chen ECJ, Chew BL Alvin , Kouretova J, Steinmetzer T, Luo D.

Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.

Antiviral Res. 2018 Dec;160:17-24. doi: 10.1016/j.antiviral.2018.10.006.

 

 

Ha N, Lai LT, Chelliah R, Zhen Y, Yi Vanessa SP, Lai SK, Li HY, Ludwig A, Sandin S, Chen L, Zhang LF.

Live-Cell Imaging and Functional Dissection of Xist RNA Reveal Mechanisms of X Chromosome Inactivation and Reactivation.

iScience. 2018 Oct 26;8:1-14.

 

 

Makhija H, Roy S, Hoon S, Ghadessy FJ, Wong D, Jaiswal R, Campana D, Dröge P.

A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression.

Nucleic Acids Res. 2018 Sep 19;46(16):e99. doi: 10.1093/nar/gky500.

 

 

Merigliano C, Mascolo E, Burla R, Saggio I, Vernì F.

The Relationship Between Vitamin B6, Diabetes and Cancer.

Front Genet. 2018 Sep 13;9:388. doi: 10.3389/fgene.2018.00388. eCollection 2018.

 

 

Sun H, Qiao Z, Chua KP, Tursic A, Liu X, Gao YG, Mu Y, Hou X, Miao Y.

Profilin Negatively Regulates Formin-Mediated Actin Assembly to Modulate PAMP-Triggered Plant Immunity.

Curr Biol. 2018 Jun 18;28(12):1882-1895.

 

 

Korolev N, Lyubartsev AP, Nordenskiöld L.

A systematic analysis of nucleosome core particle and nucleosome-nucleosome stacking structure.

Biophys J. 2018 May 22;114(10):2326-2335.

 

 

Kumar A, Mohanram H, Kong KW, Goh R, Hoon S, Lescar J, Miserez A.

Supramolecular propensity of suckerin proteins is driven by β-sheets and aromatic interactions as revealed by solution NMR.

Biomater Sci. 2018 Aug 21;6(9):2440-2447.

 

 

Koh CWQ, Goh YT, Toh JDW, Neo SP, Ng SB, Gunaratne J, Gao YG, Quakw SR, Burkholder WF, Goh WSS

Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome. 

Nucleic Acids Research, 2018, 46(22): 11659-11670. (NAR Breakthrough Article).

 

 

Shi X, Prasanna C, Nagashima T3, Yamazaki T, Pervushin K, Nordenskiöld L.

Structure and Dynamics in the Nucleosome Revealed by Solid-State NMR.

Angew Chem Int Ed Engl. 2018 Jun 14.

 

 

Phillips M, To J, Yamazaki T, Nagashima T, Torres J, Pervushin K.

Binding of a small molecule water channel inhibitor to aquaporin Z examined by solid-state MAS NMR.

J Biomol NMR. 2018 Jun;71(2):91-100.

 

 

Bogdanović N, Sundararaman L, Kamariah N, Tyagi A, Bhushan S, Ragunathan P, Shin J, Dick T, Grüber G.

Structure and function of Mycobacterium-specific components of F-ATP synthase subunits α and ε.

Journal of Structural Biology. 2018;204(3):420-34.

 

 

Gong Q, Long Z, Zhong FL, Teo DET, Jin Y, Yin Z, Boo ZZ, Zhang Y, Zhang J, Yang R, Bhushan S, Reversade B, Li Z, Wu B.

Structural basis of RIP2 activation and signaling.

Nature Communications. Nov 2018;9(1).

 

 

Su W, Kumar V, Ding Y, Ero R, Serra A, Lee BST, Wong ASW, Shi J, Sze SK, Yang L, Gao YG.

Ribosome protection by antibiotic resistance ATP-binding cassette protein.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5157-5162.

 

 

Tharakaraman K, Watanabe S, Chan KR, Huan J, Subramanian V, Chionh YH, Raguram A, Quinlan D, McBee M, Ong EZ, Tan HC, Tyagi A, Bhushan S, Lescar J, Vasudevan SG, Ooi EE, Sasisekharan R .

Rational engineering and characterization of an mAb that neutralizes Zika virus by targeting a mutationally constrained quaternary epitope.

Cell Host Microbe 23(5):618-627.

 

 

Wong YH, Kumar A, Liew CW, Tharakaraman K, Srinivasaraghavan K, Sasisekharan R, Verma C, Lescar J.

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513.

Sci Rep. 2018 May 31;8(1):8449.

 

 

Lescar J, Soh S, Lee LT, Vasudevan SG, Kang C, Lim SP.

The Dengue Virus Replication Complex: From RNA Replication to Protein-Protein Interactions to Evasion of Innate Immunity.

Adv Exp Med Biol. May 2018;1062:115-129.

 

 

Ruiz-Carrillo D, Lin J, El Sahili A, Wei M, Sze SK, Cheung PCF, Doerig C, Lescar J.

The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition.

Sci Rep. 2018 May 9;8(1):7365.

 

 

Sengar A, Vandana JJ, Chambers VS, Di Antonio M, Winnerdy FR, Balasubramanian S, Phan AT.

Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.

Nucleic Acids Res. 2018 Dec 15.

 

 

Butovskaya E, Heddi B, Bakalar B, Richter SN, Phan AT.

Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop.

J Am Chem Soc. 2018 Oct 24;140(42):13654-13662.

 

 

Lim YT, Prabhu N, Dai L, Go KD, Chen D, Sreekumar L, Egeblad L, Eriksson S, Chen L, Veerappan S, Teo HL, Tan CSH, Lengqvist J, Larsson A, Sobota RM, Nordlund P.

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

PLoS One. 2018 Dec 6;13(12):e0208273. doi: 10.1371/journal.pone.0208273. eCollection 2018.

 

 

Chatterjee D, D'Souza A, Zhang Y, Bin W, Tan SM, Bhattacharjya S.

Interaction Analyses of 14-3-3ζ, Dok1, and Phosphorylated Integrin β Cytoplasmic Tails Reveal a Bi-molecular Switch in Integrin Regulation.

J Mol Biol. 2018 Oct 19;430(21):4419-4430. doi: 10.1016/j.jmb.2018.09.008.

 

 

Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S.

Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.

Sci Rep. 2018 Sep 11;8(1):13587. doi: 10.1038/s41598-018-31850-3.

 

 

Yong HY, Luo D.

RIG-I-Like Receptors as Novel Targets for Pan-Antivirals and Vaccine Adjuvants Against Emerging and Re-Emerging Viral Infections.

Front Immunol. 2018 Jun 20;9:1379. doi: 10.3389/fimmu.2018.01379. eCollection 2018. Review.

 

 

Chen S, Larsson M, Robinson RC, Chen SL.

Direct and convenient measurement of plasmid stability in lab and clinical isolates of E. coli.

Sci Rep. 2018 Apr 11;8(1):6056. doi: 10.1038/s41598-018-23595-w.

 

 

Li Y, Zhang Z, Phoo WW, Loh YR, Li R, Yang HY, Jansson AE, Hill J, Keller TH, Nacro K, Luo D, Kang C.

Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor.

Structure. 2018 Apr 3;26(4):555-564.e3. doi: 10.1016/j.str.2018.02.005. Epub 2018 Mar 8.

 

 

Bao Q, Morshedi A, Wang F, Bhargy S, Pervushin K, Yu WP, Dröge P.

Utf1 contributes to intergenerational epigenetic inheritance of pluripotency.

Sci Rep. 2018 Jan 23;8(1):1664. doi: 10.1038/s41598-018-20336-x.

 

 

Fong J, Zhang C, Yang R, Boo ZZ, Tan SK, Nielsen TE, Givskov M, Liu XW, Bin W, Su H, Yang L.

Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa.

Sci Rep. 2018 Jan 18;8(1):1155. doi: 10.1038/s41598-018-19504-w.

 

 

Pan A, Balakrishna AM, Nartey W, Kohlmeier A, Dip PV, Bhushan S, Grüber G.

Atomic structure and enzymatic insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit C.

Free Radic Biol Med. 2018 Feb 1;115:252-265. doi: 10.1016/j.freeradbiomed.2017.12.003. Epub 2017 Dec 6.

 

 

Yan XF, Xin L, Yen JT, Zeng Y, Jin S, Cheang QW, Fong RACY, Chiam KH, Liang ZX, Gao YG.

Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein.

J Biol Chem. 2018 Jan 5;293(1):100-111. doi: 10.1074/jbc.M117.815704. Epub 2017 Nov 16.

 

 

Liu C, Liew CW, Wong YH, Tan ST, Poh WH, Manimekalai MSS, Rajan S, Xin L, Liang ZX, Grüber G, Rice SA, Lescar J.

Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.

J Bacteriol. 2018 Jan 10;200(3). pii: e00515-17. doi: 10.1128/JB.00515-17. Print 2018 Feb 1.

 

 

Puah RY*, Jia H*, Maraswami M*, Toh DFK*, Ero R*, Yang L, Patil K, Ong AAL, Krishna M, Sun R, Tong C, Huang M, Chen X, Loh TP, Gao YG, Liu DX, Chen G.

Selective Binding to mRNA Duplex Regions by Chemically Modified PNAs Stimulates Ribosomal Frameshifting.

Biochemistry, Jan 2018, 57(1):149-159.